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Many diuretic drugs used clinically inhibitNa+reabsorption in the loop of Henie. Predict the effectofthese drugs on urinary excretion of ClandK+ . Explain

-I know that since the majority of diuretics inhibitNa+transport in the ascending limb of the loop of Heniethere will beincreased concentration of Na+ excreted.Aldosterone secretion must then be triggered by the decreaseofNa+ reabsorption which then causes an increaseinNa+ reabsorption and K+ secretion intothedistal tubule and cortical collecting duct and therefor anincreasein K+ excretion. And as far as Clgoesi assume it follows the Na+ . So I beleiveurinaryexretion of Cl and K+ is increasedbydiuretics, atleast diurtetics other than the "potassiumsparing"diuretics.

I would like to know if my reasoning is correct and ifaldosteroneis indeed the major cause of excessive K+loss.Thanks

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