Question Description
Neuromuscular Junctions (chapter 11)
In vesicular transport (chapter 13) membrane “recycling” is often observed between the Cis-Golgi
network and the ER membrane ; between the late endosomes and the trans Golgi network; between
early endosomes and the plasma membrane; and between secretory vesicles and the trans Golgi
network.
What is the general purpose of this type of membrane “recycling” between compartments?
What would happens if we don’t’ recycle between early endosomes and the plasma
membrane? How would this affect the cell’s ability to obtain needed structural and energy
resources?
Figure 11-21
Describe the roles of voltage-gated; ligand-gated and mechanical gated ion channels at the
interface occurring at a neuromuscular junction (figure 11-39).
In your description mention: the role of presynaptic action potentials, membrane depolarization-
repolarization, sodium potassium pumps; calcium ion influx at presynapse; neurotransmitter
exocytosis; acetylcholine release ; post synapse; sodium ion influx; sarcoplasmic reticulum; Ca+2
efflux into cytosol and its effect on actin-myosin mediated muscle contraction (chapter 16 section on
myosin and tropomyosin troponin C etc…).
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